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Quantitative analysis of contrast-enhanced ultrasound using microbubble to detect micro-metastasis of lymph node in patients with breast cancer

Not Applicable
Recruiting
Conditions
Patients who will diagnosed with breast cancer, and will be performed radical breast surgery without neoadjuvant chemotherapy. Patients who will diagnosed with clinically negative lymph node metastasis by using preoperative palpation, CT and MRI.
Registration Number
JPRN-UMIN000023614
Lead Sponsor
Diagnostic Radiology,Tohoku University Graduate School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
90
Inclusion Criteria

Not provided

Exclusion Criteria

Patients who will have possibility of pregnancy or patients who will be breast-feeding woman. Patients who will have allergy for contrast agent of ultrasound, egg and egg products. Patients who will have right-to-left shunt. Patients who will have severe heart disease or lung disease.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate whether the quantitative measurement of blood vessel density by contrast-enhanced ultrasound enables the diagnosis of lymph nodes micrometastases in breast cancer patients by setting appropriate threshold.
Secondary Outcome Measures
NameTimeMethod
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