Donor leukapheresis for T-cell receptor gene therapy for treatment of metastatic melanoma (skin cancer)

Recruiting

• Conditions: melanoma; Skin cancer; 10040900

• Registration Number: NL-OMON34342
• Lead Sponsor: ederlands Kanker Instituut

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 2

Inclusion Criteria

Patient with a stage IV melanoma
Minimum age 18
ECOG performance status max. 1
HLA-A@-positive patients
negative for hepatitis A, B, C and HIV
Thrombocytes at least 100*109/L
Erythrocytes at least ... *109/L
Hemoglobin at least 5 mmol/L
Leukocytes at least ... *109/L
ALAT/ASAT less than three times the upper limit of normal
creatinin clearance 50ml/min or more
total bilirubin at least 20 um/L
life expectancy at least three months
patients using anticoagulans cannot attend in this study

Exclusion Criteria

NA

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Succeeding of the test runs.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>