A randomised controlled trial of a novel combination pharmacotherapy program for the treatment of cannabis dependence

Phase 2

• Conditions: cannabis dependence; Mental Health - Addiction

• Registration Number: ACTRN12609000581268
• Lead Sponsor: St Vincents, Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-07-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

using cannabis daily for at least 3 months

Exclusion Criteria

less than 18 years of age; inability to take oral medicaton; concurrent medical illness requiring acute care hospitalisation or treatment; severe renal or liver disease; pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
proportion (%) of patients achieving and maintaining abstinence from cannabis, as measured by self report and confirmed by quantitative urinalysis[at 4 weeks, and 3 and 6 months after commencing treatment]

Secondary Outcome Measures

Name	Time	Method
percentage cannabis free days as measured by Timeline Follow Back (TLFB) interview[at 4 weeks, and 3 and 6 months after commencing treatment];reduction in cannabis use (volume and $ expenditure) as measured by Timeline Follow Back (TLFB) interview[at 4 weeks, and 3 and 6 months after commencing treatment];mental health and psychosocial functioning as measured by SF-12 General Health Questionnaire, GAD 7, and K10 (Kessler Psychological Distress Scale)[at 4 weeks, and 3 and 6 months after commencing treatment]