Comparison of the effect of adding dexmedetomidine with dexamethasone to bupivacaine in abdominal transverse block on pain intensity after laparoscopic cholecystectomy

Phase 2

Recruiting

• Conditions: Other acute postprocedural pain.; Other acute postprocedural pain; G89.18

• Registration Number: IRCT20161126031095N4
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

ASA class I and II physical condition
Age between 18-65 years

Exclusion Criteria

Patient refusal to participate
Neuromuscular diseases (eg myopathy, myasthenia gravis)
Hematological diseases, bleeding or coagulation disorders
Local skin infection and sepsis at the block site
Known hypersensitivity to study drugs
Morbid obesity (BMI > -35.7
History of alcoholism or drug addiction
Any uncompensated systemic disease (cardiovascular, respiratory, metabolic, neurological and endocrine)
Other mental or emotional problems that may invalidate informed consent. Patients will be screened by a preoperative care nurse. Potentially eligible individuals will be directed to investigators for screening and additional information.
Sleep apnea or any other sleep disorder

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of patients' pain. Timepoint: zero, 2, 4, 6, 12 and 24 hours after the operation. Method of measurement: Visual Analogue Scale.;Sedation score. Timepoint: zero hours 2, 4, 6, 12 and 24 after the operation. Method of measurement: Reverse Observer Assessment Scale of Consciousness/Sedation (OAA/S).