Performance Monitoring and Response Inhibition in Cannabis Dependent Patients: An Event-Related Brain Potential Study

• Conditions: middelen afhankelijkheid; cannabis addiction; cannabis dependence

• Registration Number: NL-OMON37592
• Lead Sponsor: Erasmus Universiteit Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1) Signed informed consent
2) Age between 18 and 25 years old
3) Normal or corrected-to-normal vision (is able to read presented text in EEG task easily)
4) Being a sigaterette smoker (at least 3 sigarettes in a week);Additional criterium for patient-group
5) Meeting the DSM-IV criteria of cannabis dependence

Exclusion Criteria

1) History of significant medical illness and/or psychiatric disorders
2) Psychotropic medication
3) Alcohol use within 24 hours of the day of testing
4) Nicotine use within 3 hours of the experiment;Patient group
5) Meeting the DSM-lV criteria for dependence on other substances than nicotine or cannabis;Control group
5) Meeting the DSM-lV criteria for dependence on other substances than nicotine

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are ERP modulations in response to the Go/NoGo and<br /><br>Eriksen Flanker Task. The end of this study will be reached when 60<br /><br>participants are included and tested successfully.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To investigate whether there is a correlation with the amount and years of use<br /><br>on the one hand and the degree of errors and diminished neural correlates on<br /><br>the other hand. To investigate whether there is a correlation with the amount<br /><br>and years of use on the one hand and the degree of response inhibition on the<br /><br>other hand.</p><br>