Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

Recruiting

• Conditions: Nephrotic Syndrome
• Interventions: Other: No intervention

• Registration Number: NCT03001934
• Lead Sponsor: Sun Yat-sen University

Brief Summary

The investigators are registering all nephrotic syndrome (NS) patients regardless of the primary causes and developing a NS database in China. Patients will be followed-up and both baseline and follow-up information will be recorded in the registration system. The treatment response, longitudinal changes of renal function, renal survival, patient survival, infection events and acute kidney injury etc, will be analyzed using the NS database.

Detailed Description

The investigators are registering all NS patients regardless of the primary causes in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education), clinical characteristics (including systolic blood pressure, diastolic blood pressure, primary cause of NS, and lab measurements of serum, urine), pathological characteristics, treatment and treatment response, complications and outcomes. Patients will be followed up, the demographic, clinical characteristics, treatment, lab tests of blood and urine and complications of patients will be collected and recorded at each visit. The investigators also record the outcome at each visit, such as treatment response, longitudinal changes of renal function, hospitalization, occurrence of infection or cardiovascular events etc. The outcomes will be analyzed using the NS database.

Study Timeline

• Study Start: 2016-04
• Study First Submitted: 2016-12-21
• Study First Submitted QC: 2016-12-21
• Study First Posted: 2016-12-23
• Status Verified: 2020-10
• Last Update Submitted: 2020-10-20
• Last Update Posted: 2020-10-22
• Primary Completion: 2026-12
• Study Completion: 2028-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

• Nephrotic syndrome patients regardless of the primary causes

Exclusion Criteria

• No

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Nephrotic syndrome patients	No intervention	Patients diagnosis as nephrotic syndrome (NS)

Primary Outcome Measures

Name	Time	Method
The patient survival in NS patients	10 years

Secondary Outcome Measures

Name	Time	Method
Infection rate of NS patients	10 years
Longitudinal changes of renal function of NS patients	10 years
Renal survival in NS patients	10 years	Renal survival including end stage renal disease, dialysis, renal transplantation
Treatment response of NS patients	10 years

Trial Locations

Locations (1)

The 1st Affiliated Hospital, Sun Yet-sen University; 🇨🇳 Guangzhou, Guangdong, China