Changes in the gingival condition and inflammatory mediators of smokers who substitute the use of e-cigarettes for their regular smoking habits.

King's College London (UK)0 个研究点目标入组 20 人开始时间: 2016年2月5日最近更新: 2020年7月13日

适应症

试验速览

•1. Subjects must have at least 24 natural teeth, excluding third molars
•2. Subjects must have smoked at least 5 cigarettes/day for at least 5 years
•3. They will be systemically healthy individuals who have mild periodontal disease with no pocket depth over 5 mm at any site

•1. Subjects with any systemic condition known to exacerbate or modulate periodontal disease e.g., diabetes
•2. Have taken antibiotics in the previous 3 months
•3. Take any anti-inflammatory drugs regularly
•4. Take other medication likely to affect the periodontal tissue e.g., calcium channel blocking drugs
•5. Pregnant or nursing mothers
•6. Patients with nut allergies will be excluded as the nicotine-containing fluid may contain traces of nuts

发起方

King's College London (UK)