Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 6,317
- 试验地点
- 1
- 主要终点
- Malaria Prevalence
研究概览
简要总结
A cluster-randomized control trial will study the effect of insecticide-treated wall lining on malaria transmission in Bomi County, Liberia. Half of the villages enrolled in the study will receive insecticide-treated wall lining covering their walls and ceilings in addition to long-lasting insecticidal nets, while the other half will be protected by existing long-lasting insecticidal nets.
详细描述
Long-lasting insecticidal nets (LLINs) are the established vector control product for malaria control. In Bomi County Liberia, LLINs have been distributed but malaria prevalence in children under 5 remains high, with prevalence in study villages found to be 42% in April 2014. The major malaria vector species are resistant to pyrethroid insecticides approved for use in LLINs, and new control measures with non-pyrethroid active ingredients may protect the population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 2 Months 至 59 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Child resides in village
- •Child presents with parent or guardian
排除标准
- •Child or guardian has history of Ebola exposure
- •Child has 3 symptoms of Ebola
研究组 & 干预措施
Control
21 clusters composed of one or more villages with a total number of 30 to 70 children under 5 years old. Routine distribution of long-lasting insecticidal nets is the only malaria control intervention.
Intervention
21 clusters composed of one or more villages with a total of 30 to 70 children under 5 years old. Routine distribution of long-lasting insecticidal nets is available and in addition insecticide treated wall lining is installed in all sleeping areas with homeowner consent. All 4 walls and the ceiling are covered with lining.
干预措施: Insecticide treated wall lining (Device)
结局指标
主要结局
Malaria Prevalence
时间窗: 6 months
Tested by mRDT and PCR
次要结局
- Fever(6 months)
- Mosquito biting rate.(2 months)
- Hemoglobin(6 months)