BREATHE Registry - I Brazilian Registry of Heart Failure

Completed

• Conditions: Heart Failure

• Registration Number: NCT01428557
• Lead Sponsor: Hospital do Coracao

Brief Summary

The purpose of this study is to evaluate the demographic, clinical, prognostics characteristics of 1,200 patients admitted with clinical diagnosis of decompensate heart failure in a group of 60 hospitals representative in different regions.

Detailed Description

Background: Several local registries seek to show an isolated clinical characteristics of patients hospitalized with heart failure (HF) in hospitals and communities in Brazil. Overall, the analysis of these data suggests that there are important differences in etiology, the factors of decompensation, treatment and prognosis of HF patients in different regions.

Objectives: To evaluate the demographic, clinical, prognostics characteristics of 1,200 patients admitted with clinical diagnosis of decompensate heart failure in a group of 60 hospitals representative in different regions. Other specific objectives include describing the in-hospital mortality after admission, to describe the content and the reason for re-admission, to assess adherence to evidence-based guidelines (recommended by guidelines), to measure indicators of quality of care and establish a national registry data to allow for comparison with international records of patients admitted with ADHF.

Methods: Observational cross (record) with longitudinal follow-up where patients admitted to public and private hospitals primarily defined in IC will be studied.

Study Timeline

• Study Start: 2011-03
• Study First Submitted: 2011-09-01
• Study First Submitted QC: 2011-09-02
• Study First Posted: 2011-09-05
• Primary Completion: 2019-07
• Study Completion: 2019-09
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-19
• Last Update Posted: 2022-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3013

Inclusion Criteria

• > 18 years old,
• Boston Criteria > 7,
• patients hospitalized > 24 hours.

Exclusion Criteria

• myocardial revascularization during last month,
• heart failure due to sepsis,
• acute coronary syndrome with ventricular dysfunction as reason for current hospitalization

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total mortality	follow up at 3, 6 and 12 months

Secondary Outcome Measures

Name	Time	Method
Proportion of patients receiving interventions with proven benefit shown by different indicators of quality of care.	follow up at 3, 6 and 12 months

Trial Locations

Locations (1)

Hospital do Coracao; 🇧🇷 Sao Paulo, SP, Brazil