Towards better assessment and treatment of exercise induced wheeze

Phase 3

• Conditions: Exercise induced wheeze; Asthma; Respiratory - Asthma

• Registration Number: ACTRN12605000397617
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-09-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Exercise induced wheeze, cough or dyspnoea are the primary symptoms.

Exclusion Criteria

Current or recent ex-smokers, patients taking oral or inhaled steroids in the previous 6 weeks.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Each treatment will be deemed a success if, compared to baseline: 1. There is a >50% attenuation of any fall in FEV1 following exertion. 2. there is a 1 point improvement in the patient's Borg breathlessness scale. 3. There is a 0.5% improvement in a patient's asthma control questionnaire score. Baseline measurements will be compared with measurements taken at the conclusion of each treatment period.[At baseline and at the conclusion of each treatment]

Secondary Outcome Measures

Name	Time	Method
The predictive accuracy of each of the baseline measurements will be computed for each of the three primary outcome measures, this time measured as continuous variables. Positive and negative predictive values will be derived from ROC curve analyses.[Comparisons will be made between baseline data and data collected at the end of each treatment period.]