Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention

Completed

• Conditions: Migraine Disorders; Aphasia

• Registration Number: NCT03662295
• Lead Sponsor: Quality Living, Inc.

Brief Summary

Stroke-like migraine attacks after radiation therapy-also known as SMART syndrome-constitute a rare condition typically characterized by headache, seizures, vision abnormalities, hemiparesis, and aphasia. The condition usually resolves within a few days or weeks of onset with no residual impairments. However, resolution in some cases extends over a period of months rather than weeks and may be incomplete. The purpose of this case report is to provide an in-depth description of the progression of changes in cognitive and language functioning for a person exhibiting SMART syndrome characterized by slow recovery.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-03
• Study First Submitted: 2018-09-03
• Study First Submitted QC: 2018-09-05
• Study First Posted: 2018-09-07
• Primary Completion: 2019-11-13
• Study Completion: 2019-11-13
• Status Verified: 2021-03
• Last Update Submitted: 2021-03-09
• Last Update Posted: 2021-03-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• exhibit cognitive and language deficits secondary to SMART syndrome
• be a former or current client of Quality Living, Inc., Omaha, Nebraska
• be a native speaker of English

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Standardized assessment	Change from baseline at 6 months	Aphasia Quotient of the Western Aphasia Battery - Revised

Secondary Outcome Measures

Name	Time	Method
Written picture description	Change from baseline at 6 weeks, 10 weeks, 14 weeks, 20 weeks, and 26 weeks	Written language sample elicited through a request to write about events depicted in a Norman Rockwell drawing.
Spoken picture description	Change from baseline at 6 weeks, 10 weeks, 14 weeks, 20 weeks, and 26 weeks	Spoken language sample elicited through a request to describe events depicted in a Norman Rockwell drawing.

Trial Locations

Locations (1)

Quality Living, Inc.; 🇺🇸 Omaha, Nebraska, United States