Investigating the effect of Computerised Cognitive Training on global cognition in participants with MCI with Sleep Disturbance

niversity of Sydney0 sites62 target enrollmentJuly 10, 2018

Overview

No summary available.

Registry

who.int

Start Date

July 10, 2018

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

•Multi\-domain amnestic MCI with sleep disturbance
•Amnestic features defined by impairment in recall tasks.
•Other cognitive domains impairment on representative neuropsychological tests
•Sleep disturbance as measured by the Pittsburgh Sleep Quality Index (PSQI) 20 score of \> 5
•If using Hypnotics, sedating antihistamines, antipsychotics etc for sleep medication, use must be stable for 3\-months (any changes in sleep medication will be monitored during intervention and followup)

•History of dementia of any aetiology
•History of stroke in last 12 months
•Major neurological disorder requiring current treatment (e.g. epilepsy, Parkinson’s disease)
•Major psychiatric disorder requiring current treatment (e.g. schizophrenia, bipolar disorder)
•Current major depression as measured by the 15\-item Geriatric Depression Scale (score of \> 10\) or the 17\-item Hamilton Rating Scale for Depression (score of \> 12\)
•Physical (sensory or motor) impairment that would restrain training
•Current alcohol dependence or abuse
•Currently undertaking external computerised cognitive training and unwilling to cease during trial engagement