To compare sedative and analgesic effect of intravenous Ketamine-Propofol combination versus intravenous Ketamine-Dexmeditomidine combination in patient under going upper limb surgeries under regional anaesthesia
- Conditions
- Health Condition 1: - Health Condition 2: S599- Unspecified injury of elbow and forearm
- Registration Number
- CTRI/2020/09/027976
- Lead Sponsor
- Shree Krishna Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1) Patients ASA 1-3 physical status
2)Age 18-70 yrs of either sex
3)Patient posted for elective and emergency upper limb surgeries (in emergency surgeries NBM for 6 hour is needed , those patients are not NBM for 6 hour for solid are not included in study)
4)Patient with body mass index (BMI) 18-40 kg/m2
1)Hypersensitivity to local anesthetic agents
2)Altered mental status (phychiatric and anxiety disorder)
3)History of allergy to study drugs
4)Patient on sedative and hypnotic medications
5)Patient with chronic pain or on painkiller
6)Patient with severe hepatic or kidney impairment
7)Patient having history of thyrotoxicosis, uncontrolled hypertension, cardiac,chest or neurological diseases
8)Pregnant or breast feeding female
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RAMSAY SEDATION SCALE <br/ ><br> <br/ ><br>Quality of Sedation will be measured according to below mentioned score of RAMSAY SEDATION SCALE <br/ ><br>1) Anxious and agitated or restless ot both <br/ ><br>2) cooperative , oriented and tranquil <br/ ><br>3)Responds to command only <br/ ><br>4)Brisk response to light glabellar tap <br/ ><br>5) Sluggish response to light glabellar tap or loud auditory stimulus <br/ ><br>6)No response to light glabellar tap or loud auditory stimulusTimepoint: intraoperatively at 5,10,15,20 min......
- Secondary Outcome Measures
Name Time Method Heart rate,Respiratory rate,Blood pressure,spo2Timepoint: intraoperatively at 5,10,15,20min......