Second trimester antenatal umbilical coiling index and doppler flow characteristics and their association with perinatal outcomes.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 127
- 试验地点
- 1
- 主要终点
- Find out umbilical coiling index and doppler parameters using ultrasound.
研究概览
简要总结
PROJECT SUMMARY
The umbilical cord is the essential lifeline of fetus supplying nutrients,
oxygen and fluids necessary for life in utero. The trivascular conduit is well
protected by Whartons jelly, amniotic fluid and the helical pattern or coiling of
vessels.
Coiling of umbilical cord and its blood flow pattern has been the subject of
various anatomical and sonographic studies. These studies considered the
development, structure of umbilical cord, its blood flow pattern and assessed
utility of sonography to detect abnormal coiling and its blood flow pattern in
utero as a marker of foetal compromise.
This study will be done to determine whether abnormal umbilical cord coiling
patterns and its blood flow parameters measured sonographically between 13 to
28 weeks of gestation are associated with adverse perinatal outcomes.
NEED FOR STUDY
Very few studies have assessed blood flow
characteristics utilizing Doppler ultrasound and its association with umbilical
cord coiling index and perinatal outcome. we hypothesized
that umbilical coiling index may be associated with abnormal cord blood flow
pattern and associated with various perinatal outcome.
Hence if the coiling index and its Doppler
blood flow characteristics will be measured antenatally, it would act as a predictor
of adverse perinatal outcome.
RESEARCH QUESTION
Can second trimester umbilical coiling index and its doppler flow characteristics be used to predict adverse perinatal outcome?
AIM
To determine if any association is present between umbilical coiling index and doppler flow parameters in second trimester with adverse perinatal outcomes.
HYPOTHESIS
There is no association between umbilical coiling index and its doppler parameters measured in second trimester with adverse perinatal outcomes.
OBJECTIVES
To record umbilical coiling index and doppler flow parameters in second trimester.
To find any association between umbilical coiling index and its doppler flow parameters with perinatal outcomes.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- Female
入选标准
- •singleton pregnancy between 13 to 28 weeks of gestation.
排除标准
- •all high risk pregnancies like gestational diabetes mellitus, hypertension, Rh negative pregnancy, anomalous baby, single umbilical artery, delivery not performed at D Y Patil hospital kolhapur.
结局指标
主要结局
Find out umbilical coiling index and doppler parameters using ultrasound.
时间窗: Second trimester.
次要结局
- Find out if there is any association of umbilical coiling index & doppler parameters with adverse perinatal outcomes.(At delivery.)
研究者
Dr Houmam Khan
D Y Pati Hospital and Research Center Kolhapur