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Clinical Trials/ISRCTN22782150
ISRCTN22782150
Completed
Not Applicable

Rumination-Focused Cognitive Behavioural Therapy for residual depression: a pilot randomised controlled trial

niversity of Exeter (UK)0 sites42 target enrollmentApril 15, 2011
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ConditionsResidual treatment-resistant depressionMental and Behavioural Disorders

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Residual treatment-resistant depression
Sponsor
niversity of Exeter (UK)
Enrollment
42
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 15, 2011
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Exeter (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Aged \>18
  • •2\. Meeting criteria for medication\-refractory residual depression defined as:
  • •2\.1\. Meeting Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM\-IV) criteria for major depression within the last 18 months but not in the last 2 months
  • •2\.2\. Residual symptoms reaching at least 8 on the 17\-item Hamilton Depression Rating Scale (HRSD) and 9 on the Beck Depression Inventory (BDI\-II)
  • •2\.3\. Taking antidepressant medication at a therapeutic dose as recommended by the British National Formulary and/or equivalent to 125mg of amitriptyline for at least 8 weeks continuously during the current episode and within the last 2 months

Exclusion Criteria

  • •1\. A history of bipolar disorder, psychosis
  • •2\. Current drug or alcohol dependence
  • •3\. Learning disability
  • •4\. Organic brain damage
  • •5\. Concurrent psychotherapy at point of entry to the study
  • •There were no exclusion criteria with respect to co\-morbid anxiety disorders or Axis II diagnosis

Outcomes

Primary Outcomes

Not specified

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