SARS-CoV-2 Transmission in Belgian Primary Schools of the Federation Wallonia - Brussels: An Epidemiological Pilot Study

Active, not recruiting

• Conditions: SARS-CoV-2 Infection

• Registration Number: NCT05046470
• Lead Sponsor: Université Catholique de Louvain

Brief Summary

The investigators hypothesize that children are less likely to become infected in the school environment, compared to the household or outside the school setting. Primary schools do not play a major role in SARS-CoV-2 spreading. They hypothesize that incidence level in schools is mainly a consequence of community transmission. The incidence level in household and that the secondary attack rate in schools remains at least 5 times lower that the transmission level in households.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-14
• Study First Submitted: 2021-09-07
• Study First Submitted QC: 2021-09-15
• Study First Posted: 2021-09-16
• Primary Completion: 2023-01-14
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-07
• Last Update Posted: 2024-05-08
• Study Completion: 2025-01-14

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1233

Inclusion Criteria

• All children and school attenders from selected schools was invited to participate

Exclusion Criteria

• Refusal to provide written informed consent before enrolment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infection of an adult school-attender with SARS-CoV-2 secondary to an infected child	6 weeks	Time varying number and proportion of adult school-attenders infected with SARS-CoV-2 secondary to an asymptomatic infected child (transmission rate inside school but from a child to an adult).
Infection of a child with SARS-CoV-2 secondary to an adult school attender	6 weeks	Time varying number and proportion of children infected with SARS-CoV-2 secondary to an infected adult school-attender (transmission rate inside school but from an adult to a child)
Infection of a child with SARS-CoV-2 secondary to a classmate	6 weeks	Time varying number and proportion of children infected with SARS-CoV-2 secondary to an asymptomatic infected classmate (transmission rate inside school with the child being the infector).
Infection of a child with SARS-CoV-2 secondary to a contact outside the school, including the household	6 weeks	Time varying number and proportion of children infected with SARS-CoV-2 secondary to a household contact or outside the school (transmission rate from in community).

Trial Locations

Locations (1)

UCLouvain; 🇧🇪 Brussels, Belgium