effect of dexmedetomidine during general surgery

Phase 4

• Conditions: Health Condition 1: null- endotracheal intubation

• Registration Number: CTRI/2013/07/003820
• Lead Sponsor: Dept of Anaesthesiology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Patients posted for elective surgery under general anaesthesia requiring endotracheal intubation.

-ASA physical status I and II.

-BMI <= 25kg/m2.

-Informed written consent for participation in study.

Exclusion Criteria

-Patients with diabetes, renal disease, cardiac diseases like IHD, Hypertension.

-Patients on drugs, having effects on heart rate and blood pressure (sedatives, opioids, β blockers, calcium channel blockers) and anti-psychiatric drugs.

-Pregnant women and lactating mothers.

-Anticipated difficult intubation.

-Intubation attempt lasting longer than 20 seconds.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blunting in haemodynamic stress response during laryngoscopy and intubation.Timepoint: Blood pressure,heart rate,oxygen saturation are recorded starting from baseline to infusion and then upto 30 minutes after intubation.

Secondary Outcome Measures

Name	Time	Method
Sedative effect after infusion.Timepoint: Sedation score will be recorded baseline and then after infusion of drug till induction.