Comparative Study of Amalaki and Amalaki Loha in Anemia

Phase 2

Not yet recruiting

• Conditions: Other iron deficiency anemias. Ayurveda Condition: PANDUROGAH,

• Registration Number: CTRI/2021/11/038299
• Lead Sponsor: Dr Sadhana Rangnekar

Brief Summary

The title of study is - A Comparative Clinical Study to evaluate the efficacy of *Amalaki* and  *Amalaki Loha* in *Pandu Vyadhi.*



Anaemia is a Global publichealth problem affecting both developing and developed countries with majorconsequences on human health as well as social and economic development. Iron deficiency anaemia is by far the commonest nutritional cause of anaemia;it may be associated with a folate deficiency. Previous studies done using *Amalaki churna* haveshown results in subjective  parametersbut not as much desired effect on the objective parameters as Haemoglobin andSerum Iron levels. Using reference*, Ayas* is beneficial as mentionedin *AshtangHhridayam*. Thus, it has been decided to add *Lohabhasma* in *Amalakichurna*to evaluate and see the changes in haematological parameters. Side effects of oral allopathic iron preparations areconstipation, abdomen discomfort, heart burn, epigastric pain, nausea, vomitingetc. Thus, to get a better alternative medicine this topic isselected. *Amalaki Loha* isnot a new drug that has been discovered. It is a formulation of drugs (*anubhutayog*)having previously proven properties and can be considered as a proprietaryayurvedic medicine.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-11-24
• Study Start: 2021-11-29

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• 1. “Pandu Vyadhi†will be diagnosed on the basis of cardinal symptoms of Pandu vyadhi (Panduta, Dourbalya, Agnimandya, Akshikuta Shotha, Hritspandan) and Hemogram. 2) Age: 18-45 Yrs. Irrespective of gender, religion, Socio.
• economic status, marital status 3) Hb % more than 8 gm% & less than normal i.e. Male -<13g / dl, Female – < 12g / dl. 4) MCV less than normal. [80.

Exclusion Criteria

• 1.Known case of Endocrine disorders like Diabetes mellitus, hypothyroidism, Cushing syndrome, Chronic kidney disease.
• 2.Aplastic anaemia, sickle cell anaemia, haemophilia, thalassemia, beta Thalassemia, genetic blood disorders.
• 3.Pregnant and lactating lady.
• 4.Patient having Tuberculosis, known case of HIV, leprosy, any type of cancer.
• 5.Patient showing signs and symptoms of internal bleeding, haemorrhoids, menorrhagia, endometriosis.
• 6.Patient on immunosuppressant drugs, oral glucocorticoids.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1)To compare the efficacy of Amalaki and Amalaki Loha in Pandu vyadhi on the basis of change in haemogram and Serum Iron.	30 day
2) To compare the efficacy of Amalaki and Amalaki Loha in Pandu vyadhi on the basis of subjective parameters (Panduta, Dourbalya, Akshikutshotha, Hritspandan, Aayasena Shwas).	30 day

Secondary Outcome Measures

Name	Time	Method
1)To study in detail the results of Amalaki and Amalaki Loha in Pandu Vyadhi.	2)To study the side effects (adverse effects) of Amalaki and Amalaki Loha if any.

Trial Locations

Locations (1)

Sane Guruji Aarogya Kendra,; 🇮🇳 Pune, MAHARASHTRA, India

Sane Guruji Aarogya Kendra,

🇮🇳Pune, MAHARASHTRA, India

Dr Sadhana Suresh Rangnekar

Principal investigator

7303911704

sadhanarangnekar@gmail.com