Prevalence of Sleep Apnea Syndrome in patients with stable Chronic Heart Failure in the Dutch populatio

Completed

Conditions: sleep apnea
sleep apnea syndrome (SAS)
10019280
10046304

Registration Number: NL-OMON35928

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 100

Inclusion Criteria

•Patients with NYHA functional class II-IV stable heart failure for at least 3 months
•Patients able to understand the procedures and are willing to provide informed consent

Exclusion Criteria

•Patients aged < 18 years
•Patients who already underwent polysomnography in the previous 12 months
•History of myocardial infarction in the previous 6 months
•History of (minor) stroke in the previous 6 months
•Severe valvular dysfunction
•Severe lung disease (documented COPD GOLD 3 and 4)
•Active and/or treated malignancies within 12 months prior to inclusion
•Patients on cardial resynchronisation therapy (CRT), or scheduled for CRT
•Pregnancy or active breast feeding

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Percentage of CHF-patients without SAS, and percentage of CHF-patients with SAS<br /><br>(OSAS and CSAS). Therefore, apnea-hypopnea index (AHI) will be measured by<br /><br>polysomnography. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>From online medical patient*s files:<br /><br>Echocardiographic parameters (i.e. left ventricular ejection fraction),<br /><br>Parameters of the bicycle ergometric cardiopulmonary exercise test (Peak VO2),<br /><br>Routine blood measurements (e.g. hemoglobin-level, NT-proBNP).<br /><br><br /><br>Additional measurements:<br /><br>ApneaLink,<br /><br>Blood sample assessment,<br /><br>Urine sample assessment,<br /><br>Excessive Daytime Sleepiness (EDS). </p><br>