Early Goal-Directed Therapy Utilizing Transpulmonary Thermodilution and Severe Burn Injury

Completed

• Conditions: Burns

• Registration Number: NCT05420610
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

This study aimed to optimize fluid resuscitation with transpulmonary thermodilution (TPTD)-guided protocol and to lower the mortality rate of the severely burned.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-07
• Primary Completion: 2021-11-30
• Study Completion: 2022-01-20
• Status Verified: 2022-06
• Study First Submitted: 2022-06-07
• Study First Submitted QC: 2022-06-13
• Last Update Submitted: 2022-06-13
• Study First Posted: 2022-06-15
• Last Update Posted: 2022-06-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• Adult patients (age > 18 years).
• Major burn (as total burned surface area (TBSA) > 20% with at least second degree burn depth).
• Admitted to the intensive care unit (ICU) of the Burn Center.

Exclusion Criteria

• Patients younger than 18 years old.
• Patients with severe cardiopulmonary diseases, or associated with other major trauma.
• Patient with incomplete data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient mortality	Up to 6 months	The primary outcome was patient mortality after major burn.

Trial Locations

Locations (1)

Kaohsiung Chang Gung Memorial Hospital; 🇨🇳 Kaohsiung, Taiwan