NL-OMON26033已完成不适用
Phase 2 Study of Ascorbic Acid Treatment in Charcot-Marie-Tooth Type 1A.
Department of Neurology Academic Medical Center, University of AmsterdamP.O.Box 22660Amsterdam, Netherlands0 个研究点目标入组 12 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 12
研究概览
简要总结
Passage E, Norreel JC, Noack-Fraissignes P, Sanguedolce V, Pizant J, Thirion X, Robaglia-Schlupp A, Pellissier JF, Fontes M. Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease. Nat Med. 2004 Apr;10(4):396-401. Epub 2004 Mar 21. : 15034573;
Verhamme C, van Schaik IN, Koelman JH, de Haan RJ, Vermeulen M, de Visser M. Clinical disease severity and axonal dysfunction in hereditary motor and sensory neuropathy Ia. J Neurol. 2004 Dec;251(12):1491-7. : 15645349.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. DNA-proven CMT1A patients;
- •2. Age 12-25 years;
排除标准
- •1. Due to possible influence on severity of the neuropathy:
- •a. Known other disease that may cause a neuropathy, that may decrease mobility, or that may lead to severe disability or death in a short time;
研究者
相似试验
招募中
2 期
Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1ACharcot-Marie-Tooth disease type 1ACMT1AG600JPRN-jRCTs031190109SHIOHAMA TADASHI12
已完成
1 期
A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and EffectiveMetastatic Hepatocellular CarcinomaAdvanced Liver CancerNCT01754987Thomas Jefferson University5
尚未招募
1 期
Ascorbic acid treatment for Charcot-Marie-Tooth disease type 1AJPRN-UMIN000036332Chiba University10
终止
1 期
Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CAStage IV Colorectal CancerNCT01550510Thomas Jefferson University4
已完成
不适用
Ascorbic Acid Treatment in Charcot-Marie-Tooth Disease Type 1A (CMT1A) TrialISRCTN56968278Academic Medical Centre, Department of Neurology (Netherlands)12