CTRI/2022/12/048583
Not yet recruiting
Phase 3
Efficacy of Corticosteroid Therapy in SevereCommunity Acquired Pneumonia
GOVERNMENT MEDICAL COLLEGE AND HOSPITA0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- GOVERNMENT MEDICAL COLLEGE AND HOSPITA
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age more than 18year.
- •2\. Patients have clinical symptoms suggesting community acquired pneumonia (cough,
- •fever, pleuritic chest pain and/or shortness of breath)
- •3\. Patient who will be diagnosed as a case of severe community acquired pneumonia as per the
- •criteria ATS IDSA 2007
- •4\. Those who will give consent for study.
Exclusion Criteria
- •1\. Immunocompromised patients i.e. HIV infection, neutropenic patients(1000Ã?109
- •cell transplant recipients, patients on immunosuppressive treatment other than
- •corticosteroid, patients of leukemia/lymphoma, chronic liver disease, chronic kidney
- •disease, coronary artery disease and/ or chronic heart failure.
- •2\. Clinical suspicion of Tuberculosis
- •3\. Gastrointestinal bleeding in past three months
- •4\. Conditions requiring adjunctive long\-term corticosteroid therapy (with an equivalent dose
- •of Inj methylprednisolone 1mg/kg/d or more)
- •5\. Patients with pneumonia secondary to aspiration, hospital\-acquired infection, prior
- •treatment in ICU or receipt of mechanical ventilation.
Outcomes
Primary Outcomes
Not specified
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