The effect of omega3 supplementation in preeclampsia in pregnant women at risk in Qazvin
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 100
研究概览
简要总结
Background :Identification of factors preventing from preeclampsia in high risk pregnant women is a significant importance.Omega-3 supplementation may reduce the risk of preeclampsia.
Objective : In this research was assessed the effects of Omega-3 supplementation,on high risk pregnancy for preeclampsia in Qazvin city.
Methods:This single-blind randomized clinical trial was conducted in Qazvin city. The sample was 100 high risk pregnant women for preeclampsia(between 14-18weeks of gestation). 50were assigned to Omega-3 group and 50 to the placebo group.Women were assigned to daily supplementation with 1000mg omega-3 or placebo until delivery.Then preeclampsia and pregnancy outcome's were assessed in two groups.After employing data were recoeded and analyzed statistically using t-test,X2,mannwhitney and fisher exact test.
findings :There were significant differences between the Omega-3 and Placebo groups in the rate(p=0.015) and intensity(P=0.01) of preeclampsia.The correlation was found between the Omega-3 group and outcome of pregnancy (birth weight and Apgar score)( P=0.000,p=0.002).
Conclusion :Our results suggest that supplementation with Omega-3 during pregnancy reduced the risk of preeclampsia in high risk pregnant womenThus it seems necessary to promot educational nutritiant programs for pregnant women .
Keywords : high risk pregnancy,preeclampsia,fatty acids with long chins of omega3
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 15 years 至 45 years（—）
- 性别
- Female
入选标准
- •pregnant women whose gestational age is between 14 to 18 weeks and are ready to cooperate, being high risk for preeclampsia (first gravidy, under the age of 20 and over 40, a history of preeclampsia during the previous gravidy or immediate member of family, BMI more than 29, history of twin fetuses);
- •consumption of Aspirin, Calcium, anticoagulants, allergy to omega3 or fish, presence digestive diseases which need to treatment,
排除标准
- 未提供