Sperm selection by cumulus colum

Phase 3

• Conditions: Male infertility.; Azoospermia NOS Oligospermia NOS

• Registration Number: IRCT20180130038561N2
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Infertility couples with a male factor without varicocele diagnosis (at least one of the three sperm parameters outside the normal values ??defined by WHO) and a normal woman based on regular cycles, normal hysterosalpingogram, normal vaginal ultrasound, age under 38 years
Estradiol level below 3000 and the presence of at least 3 follicles with a size > 14 on the trigger day
Referring to the first or second cycle(s) of ICSI
Having at least 6 mature MII oocytes for ICSI
Male age less than 45 years

Exclusion Criteria

Male patients with severe male factor according to WHO criteria
Frozen sperm sample
Sperm sample obtained by aspiration or extraction from the testis
HIV positive patients
PCOS and endometriosis patients
Patients at risk of OHSS

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: Beta hCG test.

Secondary Outcome Measures

Name	Time	Method
Differences in oocyte quality between individuals. Timepoint: The quality of oocyte is checked after puncture and before in vitro fertilization. Method of measurement: Grading based on standard criteria.