JPRN-UMIN000006994
Completed
Phase 2
Phase II trial of neoadjuvant chemotherapy for unresectable liver metastasis of colorectal cancer - TAMA conversion trial (TAC trial)
Surgery, Kyorin university hospital0 sites10 target enrollmentJanuary 1, 2012
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Colorectal cancer patients with unresectable liver metastasis
- Sponsor
- Surgery, Kyorin university hospital
- Enrollment
- 10
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This clinical trial was discontinued due to a lack of case accumulation.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Patients with previous histories of severe drug hypersensitivity or drug allergies 2\) Patients with multiple primaries 3\) Patients with metastasis outside the liver and regional lymph nodes 4\) Patients with infection (fever of 38 degrees C or over) 5\) Patients with severe comobidities (interstitial pneumonia or pulmonary fibrosis, cardiac failure, renal failure, liver failure, uncontrollable diabetes or hypertension, jaundice) 6\) Patients with pleural effusion or ascites requiring treatment 7\) Patients with diarrhea (watery) 8\) Patients receiving atazanavir sulfate or flucytosine treatment 9\) Pregnant women and women suspected of being pregnant and lactating women 10\) Patients evaluated as unsuitable for this trial by the doctor in charge 11\) Patients with arterial or venous thrombosis in KRAS mutant cases
Outcomes
Primary Outcomes
Not specified
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