Rajaie Cardiomyopathy and Myocarditis Registry
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 6,000
- 试验地点
- 1
- 主要终点
- Incidence of sudden death
研究概览
简要总结
The prevalence of patients with cardiomyopathies who referred to Rajaei Cardiovascular medical and research center is remarkable, and also the mission of this center is to achieve center of excellence in the field of cardiomyopathy. Rajaie Cardiomyopathy and myocarditis Registry study is an observational registry of consecutive patients with four cardiomyopathy subtypes: hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), and restrictive cardiomyopathy (RCM) as well as myocarditis designed to determine clinical characteristics, natural history, current therapeutic approaches, response to treatment and long-term outcomes of patients with cardiomyopathy and myocarditis and to address limitations in extant evidence to improve prognostication in cardiomyopathies and myocarditis. Prediction of mortality and response to different treatments in these patients using artificial intelligence is another aim of this registry
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age greater than one year
- •documented cardiomyopathy/ myocarditis fulfilling standard diagnostic criteria
- •able to give informed consent or in the case of child consent from a parent
排除标准
- •Patients who have not consent to participate in the study.
结局指标
主要结局
Incidence of sudden death
时间窗: 1 year
unexpected death from a cardiovascular cause in a person with or without preexisting heart disease
Admissions to hospital
时间窗: 1 year
Number of hospitalizations for cardiovascular reasons
Development of chronic heart failure
时间窗: 1 year
significant decrease in left ventricular ejection fraction
Incidence of heart trasplantation
时间窗: 1 year
Cardiac transplantation in patients with end-stage HF who remain symptomatic despite optimal medical therapy
Prevalence of Stroke/Transient ischemic attack
时间窗: 1 year
At least 80% CT/MRI verification of the diagnosis of ischemic stroke/Transient ischemic attack, within the first week of stroke onset
次要结局
- response to current therapeutic approaches(1 year)