Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Covid19
- Sponsor
- Murielle Surquin
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Demographic data
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
SARS-CoV2 or CoVid19 disease is a newly described pathology linked to a subtype of the coronavirus family identified in China in December 2019. This pathology can present multiple clinical facets, ranging from asymptomatic forms to more commonly critical pulmonary forms called "Acute Respiratory Distress Syndrome". The elderly population is more at risk for this infection due to the senescence of the immune system, co-morbidities and poly medications. They also often present a greater state of fragility.
This study aims to report the epidemiology of the first 50 patients over 90 years of age hospitalized within the CHU Brugmann hospital.
Investigators
Murielle Surquin
Head of geriatry department
Brugmann University Hospital
Eligibility Criteria
Inclusion Criteria
- •Be over 90 years of age on the date of admission to CHU Brugmann Hospital
- •Have a SARS Cov2 infection proven by antigen or RT-PCR on smear and / or typical imaging regardless of the clinical manifestation
- •Have been hospitalized at CHU Brugmann between 03/01/2020 and 05/10/2020
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Demographic data
Time Frame: 5 minutes
Age, sex, ethnicity
CK
Time Frame: 5 minutes
CK at hospital admission or first recorded
Troponin
Time Frame: 5 minutes
Troponin at hospital admission or first recorded
Number of pulmonary lobes affected
Time Frame: 5 minutes
Number of pulmonary lobes affected
Comorbidities
Time Frame: 5 minutes
Smoking, Obesity, Diabetes, Arterial hypertension, Coronary pathology, Cerebrovascular disease, chronic renal failure, chronic obstructive pulmonary disease, Neoplasia, Autoimmune disease, Chronic liver disease
Gasometry
Time Frame: 5 minutes
Vital signs at hospital admission: Gasometry
Blood count
Time Frame: 5 minutes
Blood count at hospital admission or first recorded
Coagulation
Time Frame: 5 minutes
Coagulation at hospital admission or first recorded
Renal function
Time Frame: 5 minutes
Renal function at hospital admission or first recorded
Albumin
Time Frame: 5 minutes
Albumin at hospital admission or first recorded
Ionogram
Time Frame: 5 minutes
Ionogram at hospital admission or first recorded
NTproBNP
Time Frame: 5 minutes
NTproBNP at hospital admission or first recorded
Length of ICU Stay
Time Frame: 5 minutes
Length of ICU Stay
Procalcitonin
Time Frame: 5 minutes
Procalcitonin at hospital admission or first recorded
Treatments
Time Frame: 5 minutes
Under Chronic corticosteroid therapy or Immunosuppressive therapy
Hypotension
Time Frame: 5 minutes
Vital signs at hospital admission: Hypotension
Infectious data
Time Frame: 5 minutes
Contact with confirmed covid person before admission, lives in a retirement home with other cases, Initial bacterial or viral co-infection, Bacterial or viral co-infection during the hospital stay
D-dimers at hospital admission or first recorded
Time Frame: 5 minutes
D-dimers
Status at hospital exit
Time Frame: 5 minutes
One of the following choices: death, went back home, went back to a retirement home, was placed in a revalidation unit.
Treatment received
Time Frame: 5 minutes
Hydroxychloroquine or Azithromycin
Liver function
Time Frame: 5 minutes
Liver function at hospital admission or first recorded
Fibrinogen
Time Frame: 5 minutes
Fibrinogen at hospital admission or first recorded
Fever
Time Frame: 5 minutes
Vital signs at hospital admission: Fever
Hypoxemia
Time Frame: 5 minutes
Vital signs at hospital admission: Hypoxemia
Tachycardia
Time Frame: 5 minutes
Vital signs at hospital admission:Tachycardia
Mortality
Time Frame: 5 minutes
28-day mortality after PCR / CT scan / diagnosis
Cumulative Illness Rating Scale-Geriatric (CIRS-G)
Time Frame: 5 minutes
CIRS-G quantifies burden of disease in elderly patients (comorbidity scale). Higher scores indicate higher severity (maximum score = 56 points).
Signs and symptoms
Time Frame: 5 minutes
Presence and date of first apparition: Fever, Cough, Dyspnea, Chest pain, Nausea or vomiting, Diarrhea, Fatigue, Anosmia, ageusia, inappetence, Confusion, Fall, Fracture
CRP
Time Frame: 5 minutes
CRP at hospital admission or first recorded
Ferritin
Time Frame: 5 minutes
Ferritin at hospital admission or first recorded
Biology - highest rate
Time Frame: 5 minutes
Highest rate of CRP, D-Dimers, Urea, Creatinin, Fibrinogen, CK, Troponins
Biology - lowest rate
Time Frame: 5 minutes
Lowest rate of hemoglobin, platelets, leucocytes, lymphocytes, albumin, Na+, K+
Percentage of pulmonary involvement on chest CT scan
Time Frame: 5 minutes
Percentage of pulmonary involvement on chest CT scan
Type of lesions
Time Frame: 5 minutes
Type of lesions as reflected on the CT scan images: 'Ground glass' or 'Crazy paving'
Need for oxygenotherapy
Time Frame: 5 minutes
Need for oxygenotherapy (yes/no)
Means of ventilation
Time Frame: 5 minutes
Means of ventilation