Characterization of the role of blood circulation and neovascularization in acute and chronic pruritus - iETOP

Charité - Universitätsmedizin Berlin0 个研究点目标入组 40 人开始时间: 2015年7月10日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Inclusion criteria healthy subjects:
•The volunteers must be over eighteen, and be able to communicate with the investigator. They must be able to understand the contents of the study and they need to consent to participate in the study. Only male subjects.
•Inclusion criteria patients:
•1. Signed informed consent
•2. Prurigo patients with chronic pruritus (> 6 months) and a severity of prurigo using VAS = 6/10
•3. The patient willing to only use the mentioned products and no other own externa. As rescue medication in severe itching, patients receive a care cream DAC base cream that can be applied as often as desired.
•4. Of full age
•5. Both male and female patients

•Exclusion criteria subjects:
•Known history of hypersensitivity to any of the substances to be applied.
•Regular or current intake of medications against itch such as antihistamines, topical or systemic steroids, immunosuppressants or gabapentin.
•Participation in a clinical trial in the last 30 days.
•Exclusion criteria patients:
•1. Therapeutic UV radiation during the last 6 weeks before the start of the investigation or during the investigation
•2. Topical antihistamines, steroids or mast cell stabilizers in the last 3 weeks prior to the study or during the study
•3. Systemic medications such antihistamnika, antidepressants, antipsychotics, corticosteroids are permitted if:
•a) the medication were taken since at least the last 4 weeks prior to the study and
•b) there has been no changes regarding the use or dosage during the study
•4. A history of hypersensitivity to any of the substances to be applied
•5. Diseases that does not allow to include patients in the study, assessed by the investigator
•6. Pregnant or lactating women or planned pregnancies during the study
•7. Participation in another study in the last 30 days.

发起方