Relationship Between Indexed Aortic Area and Aortic Diameter in Bicuspid Aortic Valve Aortopathy: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 69
- 试验地点
- 1
- 主要终点
- Cross-sectional aortic area/patient height ratio in aneurysms
研究概览
简要总结
This study aims to determine the relationship between the cross-sectional aortic area/patient height ratio (indexed aortic area) and absolute aortic diameter in proximal thoracic aortic aneurysms associated with a bicuspid valve. This will shed light on whether aneurysms with smaller diameters than those recommended for surgical intervention by guidelines are still at risk of aortic complications attending an abnormally high indexed aortic area.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years
- •First-time surgery
- •Bicuspid aortic valve confirmed
- •Thoracic aortic aneurysm involving aortic root or ascending aorta
排除标准
- •No available pre-operative cross-sectional imaging
- •Re-do surgery
结局指标
主要结局
Cross-sectional aortic area/patient height ratio in aneurysms
时间窗: Data collection period from 27th January 2017 - 15th May 2017
Calculation of indexed aortic area in aneurysms
Median cross-sectional aortic area/patient height ratio for aneurysms with diameter <4.0 cm, 4.0-4.5 cm, 4.5-5.0 cm, 5.0-5.5 cm and >5.5 cm
时间窗: Data collection period from 27th January 2017 - 15th May 2017
Median aortic diameters in aneurysms
时间窗: Data collection period from 27th January 2017 - 15th May 2017
As above
Median aortic diameter corresponding to aneurysms with IAA >10 cm2/m
时间窗: Data collection period from 27th January 2017 - 15th May 2017
Proportion of aneurysms with cross-sectional aortic area/patient height ratio >10 cm2/m
时间窗: Data collection period from 27th January 2017 - 15th May 2017
Proportion of aneurysms with an abnormal indexed aortic area
次要结局
未报告次要终点
研究者
Metesh Acharya
Mr Metesh Acharya
St. George's Hospital, London