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Clinical Trials/NCT00612482
NCT00612482
Completed
Phase 1

Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education: A High School Pilot Study

Boston Children's Hospital1 site in 1 country225 target enrollmentDecember 2006
ConditionsSubstance Abuse

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Substance Abuse
Sponsor
Boston Children's Hospital
Enrollment
225
Locations
1
Primary Endpoint
Lifetime, past 6 month and past 30 day use of substances
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum. Through this pilot study we propose to: (1) demonstrate that this new strategy shows promise, and (2) estimate the effect size for the intervention.

Detailed Description

NIDA, in recent years, has put resources into summarizing and synthesizing cutting-edge medical and basic science research discoveries about the short-term and long-term effects of drug use on the developing brain. One outcome of this results was the production of a science-based drug education program entitled "The Brain: Understanding Neurobiology Through the Study of Addiction." This is a 5-lesson module for high school science classes that teaches about brain structure and function, how drugs affect and change the biology and chemistry of the brain, how addiction occurs in the brain, and that addiction is a chronic, recurring disease. However, the effect of receipt of this program on students' substance use knowledge, attitudes, perceived risk of harm, and behavior has not been systematically evaluated to date. The specific aims of this project are: 1. To evaluate the effects of receipt of the curriculum on specific cognitive contributors to substance use including a)students' knowledge about the short- and long-term effects of substance use on the brain; b)perceived risk of harm from substance use; and c)intention to use substances in the next 3 months. 2. To evaluate the effects of the intervention on actual substance use behavior. We hypothesize that the effectiveness of this approach may be modified by the students' level of prior and current substance use, with the effect being stronger among those who have not already initiated use, or among those who have very low use. Therefore, we will specifically examine whether the intervention a)prevents substance use initiation among students who had no previous use, b)stops use among students with low lifetime use, and c) reduces use among those with higher levels of use.

Registry
clinicaltrials.gov
Start Date
December 2006
End Date
January 2008
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Student in 9th/10th/11th grade science classes at Fenway High School at start of study or student in 11th grade science classes at Boston Arts Academy at start of study
  • Parental permission to participate

Exclusion Criteria

  • No parental permission to participate
  • Unable to read English

Outcomes

Primary Outcomes

Lifetime, past 6 month and past 30 day use of substances

Time Frame: Pre-intervention, immediate post-intervention, 6-7 month post-intervention

Secondary Outcomes

  • Frequency and quantity of substance use(Pre-intervention, immediate post-intervention, 6-7 months post-intervention)
  • Knowledge about effects of substance use on the brain(Pre-intervention, immediate post-intervention, 6-7 months post-intervention)
  • Perceived risk of harm of substance use(Pre-intervention, immediate post-intervention, 6-7 months post-intervention)
  • Intention to use substances in the next 3 months(Pre-intervention, immediate post-intervention, 6-7 months post-intervention)

Study Sites (1)

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