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Risk stratification in Brugada syndrome: analysis of unipolar Holter electrocardiogram after Pilsicainide provocation.

Not Applicable
Conditions
Brugada syndrome
Registration Number
JPRN-UMIN000035530
Lead Sponsor
Department of Medicine 2 Kansai Medical University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients with bundle branch block. 2)Patients with left ventricular dysfunction and/or structural heart diseases. 3) Patients who have an invasive therapy for other disease. 4) Patients who cannot undergo Holter ECG. 5) Patients who rejected the inclusion in this study.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate late potentials [LP: filtered QRS(f-QRS), duration of low-amplitude signals :LAS40 and root mean square voltage:RMS40], ST amplitude(mV), QTc interval, J amplitude and T-wave alternans (TWA) in leads V2 and V5 on unipolar Holter electrocardiogram after the plisicainide provocation.
Secondary Outcome Measures
NameTimeMethod
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