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Clinical Trials/NCT07526831
NCT07526831
Recruiting
Not Applicable

Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Block Combined With Local Anesthetic Infiltration Between the Popliteal Artery and the Capsule of the Knee (IPACK) in Patients Undergoing Knee Surgery

TC Erciyes University2 sites in 1 country60 target enrollmentStarted: April 15, 2026Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
60
Locations
2
Primary Endpoint
opioid consumption

Overview

Brief Summary

To evaluate the effectiveness of Adductor Canal Block and combined Adductor Canal plus IPACK block in reducing postoperative pain and analgesic requirements in patients undergoing knee surgery.

Detailed Description

In total knee arthroplasty, ultrasound-guided Adductor canal block or Adductor Canal block combined with local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) will provide adequate postoperative analgesia.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Other

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • ASA (American Society of Anesthesiologists) I- ASA II-ASA III Patients

Exclusion Criteria

  • history of allergy to the study medication
  • refusal to participate

Arms & Interventions

Adductor canal block group(ACB)

Patients in the ACB group (Group I) will receive a single-shot adductor canal block under ultrasound guidance bupivacaine administered preoperatively.

Intervention: Adductor Canal Block Group (Group I) (Procedure)

Adductor canal + iPACK block group(ACB+IPACK)

Patients in the ACB + iPACK group (Group II) will receive a single-shot adductor canal block combined with an infiltration between the popliteal artery and the capsule of the knee (iPACK) under ultrasound guidance bupivacaine.

Intervention: Adductor Canal + iPACK Block Group (Group II)" (Procedure)

Outcomes

Primary Outcomes

opioid consumption

Time Frame: 24 hours after surgery

In the recovery room, all patients will given a patient- controlled analgesia device containing morphine 0.5 mg/ml, set to deliver a 1mg bolus dose of morphine with an 15 min lockout time and 4 mg 1 h limit.Total morphine consumption during the 24 hours postoperative period will recorded at 5 times intervals ( 2, 4, 6, 12, 24 hours).

Verbal analog Pain Scores on rest and movement

Time Frame: 24 hours after surgery

A Research assistant, blinded to the group allocation, interviewed patients and collected data at 5 times intervals ( 2, 4, 6, 12, 24, hours) in the 24 hours postoperatively. Patients were asked to rate their pain using verbal analog scale, where 0= no pain and 10= worst pain possible.

Secondary Outcomes

  • incidences of adverse effects (like nausea and vomiting)(24 hours after surgery)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Sibel Seçkin Pehlivan

Teaching Assistant

TC Erciyes University

Study Sites (2)

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