Relationship Between Metabolic Syndrome and Obstructive Sleep Apnea
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sleep Apnea
- Sponsor
- Cairo University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Predictors of metabolic syndrome among OSA patients
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Background:Metabolic syndrome is a disorder characterized by abdominal obesity,hypertension,increased triglycerides ,decreased HDL cholesterol and increased blood glucose. Accumulating evidence strongly indicates that insulin resistance and an increased amount of abdominal fat are the pathogenic factors for the characteristics of metabolic syndrome. Studies indicate that sleep apnea may be a manifestation of the metabolic syndrome.
Subjects and methods:This study was conducted in the pulmonology department at kasrelainy hospital. It included 80 patients who came to the sleep lab unit for polysomnography. Each patient was subjected to full history taking including(sex,age,smoking history,presence of diabetes or hypertension),thorough clinical examination with emphasis on waist, neck&hip circumference and blood pressure measurements,Laboratory investigations including :Lipid profile& Diabetic profile(HBA1C).In addition to ESS and stop bang score questionnaire.
Investigators
Eman Kamal Ibrahim Hassan
Assistant Professor of pulmonology
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Patients fulfilled the criteria of OSA ( obstructive sleep apnea) in the form of symptoms suggestive of OSA (daytime sleepiness/daytime fatigue/headache/snoring)and with AHI ( apnea-hyponea index) ≥5.
Exclusion Criteria
- •Cerebro-vascular accident within the preceding 30 days.
- •Patients on sedatives.
- •Patients on anti-psychotics
Outcomes
Primary Outcomes
Predictors of metabolic syndrome among OSA patients
Time Frame: 6 months
evaluation of factors related to occurrence of metabolic syndrome in OSA such as age(in years),weight in kilograms(kg) and height in meters (m) will not be measured separately but combined to assess BMI( weight in kg/ height in m2) and oxygen saturation (O2%), evaluation of polysomnographic data and laboratory tests in the form of lipid profile in (mg/dl) and HBA1C (g/dl)