Metabolic Syndrome and Obstructive Sleep Apnea

Completed

• Conditions: Sleep Apnea; Metabolic Syndrome
• Interventions: Diagnostic Test: sleep study

• Registration Number: NCT06051097
• Lead Sponsor: Cairo University

Brief Summary

Background:Metabolic syndrome is a disorder characterized by abdominal obesity,hypertension,increased triglycerides ,decreased HDL cholesterol and increased blood glucose. Accumulating evidence strongly indicates that insulin resistance and an increased amount of abdominal fat are the pathogenic factors for the characteristics of metabolic syndrome. Studies indicate that sleep apnea may be a manifestation of the metabolic syndrome.

Subjects and methods:This study was conducted in the pulmonology department at kasrelainy hospital. It included 80 patients who came to the sleep lab unit for polysomnography. Each patient was subjected to full history taking including(sex,age,smoking history,presence of diabetes or hypertension),thorough clinical examination with emphasis on waist, neck\&hip circumference and blood pressure measurements,Laboratory investigations including :Lipid profile\& Diabetic profile(HBA1C).In addition to ESS and stop bang score questionnaire.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-01
• Primary Completion: 2023-03-31
• Study Completion: 2023-05-15
• Status Verified: 2023-09
• Study First Submitted: 2023-09-04
• Study First Submitted QC: 2023-09-18
• Last Update Submitted: 2023-09-18
• Study First Posted: 2023-09-22
• Last Update Posted: 2023-09-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients fulfilled the criteria of OSA ( obstructive sleep apnea) in the form of symptoms suggestive of OSA (daytime sleepiness/daytime fatigue/headache/snoring)and with AHI ( apnea-hyponea index) ≥5.

Exclusion Criteria

1. Cerebro-vascular accident within the preceding 30 days.
2. Patients on sedatives.
3. Patients on anti-psychotics

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
OSA with metabolic syndrome	sleep study	sleep study
OSA without metabolic syndrome	sleep study	sleep study

Primary Outcome Measures

Name	Time	Method
Predictors of metabolic syndrome among OSA patients	6 months	evaluation of factors related to occurrence of metabolic syndrome in OSA such as age(in years),weight in kilograms(kg) and height in meters (m) will not be measured separately but combined to assess BMI( weight in kg/ height in m2) and oxygen saturation (O2%), evaluation of polysomnographic data and laboratory tests in the form of lipid profile in (mg/dl) and HBA1C (g/dl)

Trial Locations

Locations (1)

Kasr alainy school of medicine; 🇪🇬 Cairo, Egypt