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Telehealth Virtual Reality Exergaming for Spinal Cord Injury

Not Applicable
Withdrawn
Conditions
Spinal Cord Injuries
Interventions
Behavioral: Virtual Reality Gaming
Registration Number
NCT05318079
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

This pilot feasibility study aims to test whether youth and adults with spinal cord injury can use a group virtual reality gaming intervention to exercise. A second purpose is to examine whether there are potential benefits to cardiometabolic health and psychosocial health.

Detailed Description

There are three purposes to this study.

The first purpose is to quantify feasibility through telemonitored exercise data: total play time, moderate exercise time, playtime with others, and compliance to the data collections. These variables will be compared against a priori criteria for acceptability. These variables will help determine whether modifications to the intervention protocol are necessary.

The second purpose is to qualitatively interview participants to explain underlying behavioral mechanisms that affect their participation in the program. This information will be used to explain how to improve implementation issues identified in Aim 1.

The third aim is to explore the potential effects of the program on self-reported psychosocial health and quality of life, hand-grip strength, and cardiometabolic health (blood cholesterol, lipids, pressure, and insulin) measured via home dried blood spot test.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • medical diagnosis of traumatic spinal cord injury (determined by International Classification of Disease [ICD] codes)
  • a caregiver to support the participant if the participant is a child (<18 years of age)
  • access to a Wi-Fi Internet connection in the home
Exclusion Criteria
  • physically active (defined as >150 minutes per week of moderate-to-vigorous intensity exercise in a typical week)
  • cannot use the arms for exercise or operate the controller buttons using their fingers
  • complete blindness or deafness
  • recent myocardial infarction or electrocardiography changes, complete heart block, acute congestive heart failure, unstable angina, and uncontrolled severe hypertension [BP >/= 180/110 mmHg]
  • prone to seizures

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group virtual reality gamingVirtual Reality GamingThe intervention will include home-based exercise using the Oculus Quest 2. Participants will be prescribed two gaming goals to achieve across the 8-week intervention. The first goal will be to play with the Quest for at least ≥60 minutes, 5 days per week (Monday - Friday) across the 8-week intervention: a total of 300 minutes. Participants can achieve these goals through either single- or multiplayer gaming but will be prescribed to engage in online multiplayer or peer-to-peer gaming at least 2 days per week.
Primary Outcome Measures
NameTimeMethod
Total play timeIntervention Week 1 - Week 8

Percentage of the 300 minutes of prescribed play per week across the intervention.

Total exercise timeIntervention Week 1 - Week 8

Moderate exercise minutes where prescription was met (percent of prescription achieved: weeks where the ≥90 minutes of moderate intensity exercise per week was achieved across the intervention, divided by total weeks).

Compliance to post data collectionsWeek 9

Number of pre data collections completed, converted into a percentage dividing by the total possible.

Compliance to baseline data collectionWeek 0

Number of pre data collections completed, converted into a percentage dividing by the total possible.

Playtime with othersIntervention Week 1 - Week 8

Measured by the number of play sessions with other players (online multiplayer and/or peer-gaming). This number will be totaled across the 8-week intervention and divided by 16 (the exercise prescription of 2 x per week of multiplayer gaming).

Secondary Outcome Measures
NameTimeMethod
Changes in blood pressureWeek 0, Week 5, Week 9

Changes in resting home-blood pressure (systolic and diastolic ) measured via blood pressure cuff across the intervention.

Changes in high sensitivity C-reactive protein (hsCRP)Week 0, Week 5, Week 9

Changes in high sensitivity C-reactive protein measured via blood spot test across the intervention.

Changes in low-density lipoprotein (LDL)Week 0, Week 5, Week 9

Changes in low-density lipoprotein via blood spot test across the intervention.

Changes in hemoglobin A1cWeek 0, Week 5, Week 9

Changes in hemoglobin A1c measured via blood spot test across the intervention.

Functional Grip StrengthWeek 0, Week 5, Week 9

Grip strength will be measured as an indicator of global muscular strength, using a low-cost hand-held dynamometer.

Changes in fasting insulinWeek 0, Week 5, Week 9

Changes in fasting insulin levels measured via blood spot test across the intervention.

Changes in total cholesterolWeek 0, Week 5, Week 9

Changes in total cholesterol measured via blood spot test across the intervention.

Critical factors that affected adherenceIntervention Week 9

Participants will undergo one-on-one, semi-structured interviews after the intervention to identify critical factors that affected their participation to the intervention.

Hospital Anxiety and Depression ScaleWeek 0, Week 5, Week 9

The Hospital Anxiety and Depression Scale is a 14-item self-report measure that provides separate scores for anxiety and depression. Hospital Anxiety and Depression Scale is a common clinical measure that has strong psychometric properties. Scores range from 0 to 42, where a higher score represents a worse level of depression.

World Health Organization Quality of LifeWeek 0, Week 5, Week 9

The World Health Organization Quality of Life is a self-report questionnaire with 26 items that cover 5 dimensions: physical health (7 items); psychological health (6 items); social relationships (3 items); environment (8 items); and overall quality of life (2 items). Raw scores are calculated for each domain on a lilkert scale of 1-5 (low domain score of 3, max domain raw score of 40. Raw scores are then multiplied by 4 to transform the raw score into a scaled score. Higher scores represent higher perceived ratings of quality of life.

Changes in fasting triglyceridesWeek 0, Week 5, Week 9

Changes in fasting triglycerides levels measured via blood spot test across the intervention.

Changes in high-density lipoprotein (LDL)Week 0, Week 5, Week 9

Changes in high-density lipoprotein via blood spot test across the intervention.

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