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Clinical Trials/NCT06138314
NCT06138314
Completed
Not Applicable

A Feasibility and Acceptability Study of a Physical Exercise Program Including Neural Mobilization to Improve Pain, Functional Status, and Physical Performance in Older Adults With Chronic Musculoskeletal Pain

Aveiro University1 site in 1 country30 target enrollmentFebruary 12, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Musculoskeletal Pain
Sponsor
Aveiro University
Enrollment
30
Locations
1
Primary Endpoint
Dropout and adherence rates
Status
Completed
Last Updated
last year

Overview

Brief Summary

The goal of this pilot study is to evaluate the feasibility of integrating neural mobilization techniques into a multimodal physical exercise program for older adults with chronic musculoskeletal pain. The main questions it aims to answer are:

  • What is the average time to assess secondary outcomes for each participant?
  • What proportion of participants adhered and/or withdrew from the study at the end of the intervention protocol?
  • Are there adverse events/effects associated with the intervention protocol?
  • What is the level of approval/satisfaction of the participants in relation to the assessment and intervention protocols?
  • What is the impact of the intervention protocol on participants´ pain, function, physical performance, somatosensory function, and nerve excursion (secondary outcomes)?

Participants will be assessed at 3 different moments: initial assessment (T0), at the end of the intervention protocol (8 weeks) (T1) and 3 months after the end of the intervention protocol (T2). The intervention protocol will consist of a multimodal exercise program (with or without integration of neural mobilization techniques) to be carried out over a period of 8 weeks at a frequency of twice a week.

Registry
clinicaltrials.gov
Start Date
February 12, 2024
End Date
July 13, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Aveiro University
Responsible Party
Principal Investigator
Principal Investigator

Frederico Mesquita Baptista

Principal Investigator

Aveiro University

Eligibility Criteria

Inclusion Criteria

  • Community-dwelling older adults aged 60 years or older, with primary or secondary chronic musculoskeletal pain in any body site and able to walk independently

Exclusion Criteria

  • Individuals with post-surgical pain as a result of surgery performed in the last 6 months;
  • Patients with a self-reported diagnoses of infection diseases, dementia, tumor/cancer, neurodegenerative diseases, stroke, uncontrolled diabetes, or at high risk of developing cardiovascular events;
  • Those with physical limitations that make it impossible for them to carry out the intervention protocols independently (e.g., wheelchair user);
  • Patients who are receiving another physical therapy intervention to treat their pain.

Outcomes

Primary Outcomes

Dropout and adherence rates

Time Frame: T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment)

Proportion of participants who adhered and withdrew from the study at the end of the intervention protocol. "Adherence to treatment" will be considered if the participant attends at least 12 sessions (75% of the total scheduled sessions).

Adverse events and adverse effects

Time Frame: T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment)

Proportion of participants that reported adverse events and adverse effects during the intervention protocol.

Practicality

Time Frame: T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment)

The average time taken to assess secondary outcomes for each participant.

Acceptability

Time Frame: T1: 8 weeks (post-intervention assessment)

The degree to which participants approve of or are satisfied with the assessment and intervention protocols. Acceptability will be assessed qualitatively through focus groups, where a recorded interview (audio only) will be carried out by the study's main researcher, in order to assess the participants' perception of the study and the intervention protocol.

Secondary Outcomes

  • Lower Limb Strength(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Grip Strength(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Neuropathic pain components(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Fear of Movement(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Temporal characteristics of pain(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Symptoms of Central Sensitization(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Pressure Pain Threshold (Thenar region of the right hand; Right calcaneus; Region of greatest pain)(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Pain severity(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Pain Catastrophizing(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Cold and Warm Perception Threshold ((Thenar region of the right hand; Right calcaneus; Region of greatest pain)(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Agility and Dynamic Balance(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Nerve excursion (median and tibial nerves)(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))
  • Range of Motion (ankle dorsiflexion and wrist extension)(T0: baseline assessment; T1: 8 weeks (post-intervention assessment); T2: 3 months post-intervention (follow-up assessment))

Study Sites (1)

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