A Study on the Relationship Between Gastric Xanthoma and Gastric Cancer and Precancerous Lesions

Completed

• Conditions: Helicobacter Pylori Infection; Gastric Xanthoma; Intestinal Metaplasia; Precancerous Lesions; Gastric Cancer

• Registration Number: NCT06282484
• Lead Sponsor: Xijing Hospital of Digestive Diseases

Brief Summary

To explore the effects of gastric xanthoma on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.

Detailed Description

This is a large-scale single center case-control study. Patients were consecutively enrolled and divided into gastric cancer group, gastric precancerous lesions group, and chronic gastritis group, according to histopathological results.Record the location and quantity of gastric xanthoma and situation of Helicobacter pylori infection in each patient.

Study Timeline

• Study Start: 2022-09-01
• Primary Completion: 2023-06-01
• Study Completion: 2023-09-29
• Status Verified: 2024-02
• Study First Submitted: 2024-02-21
• Study First Submitted QC: 2024-02-21
• Last Update Submitted: 2024-02-21
• Study First Posted: 2024-02-28
• Last Update Posted: 2024-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1260

Inclusion Criteria

1. Age range from 18 to 75 years old, regardless of gender;
2. Endoscopic/pathological diagnosis: chronic non atrophic gastritis/chronic atrophic gastritis/intestinal metaplasia/dysplasia Hyperplasia/gastric cancer
3. Voluntarily sign an informed consent form.

Exclusion Criteria

1. Previously underwent upper gastrointestinal surgery
2. Previous diagnosis of malignant tumors
3. Individuals who are unable to cooperate with the questionnaire survey due to mental disorders or other reasons
4. Those who cannot be observed by endoscopy due to acute upper gastrointestinal bleeding or other reasons

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
corelation between the gastric xanthoma and gastric mucosa diseases	up to 6 months	we evaluate the corelation between the gastric xanthoma and gastric mucosa diseases according to the histopathological results and the scales the patients finished

Trial Locations

Locations (1)

Xijing Hosipital of Digestive Disease; 🇨🇳 Xi'an, Shaanxi, China