CTRI/2024/03/064278尚未招募Phase 3 4
Efficacy of N Acetyl Cysteine in the management of Zinc Phosphide Rodenticide Poisoning and its outcomes: A Randomized Double Blinded Controlled Trial
J.L.N Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年3月30日最近更新:
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To study the efficacy of N acetyl cysteine in management of zinc phosphide rodenticide poisoning in reducing morbidity and mortality in patients
研究概览
简要总结
In this study, we will compare clinical profile and biochemical outcomes in the patients of acute zinc phosphide poisoning management by using Inj N Acetyl Cysteine as an adjuvant at the emergency medicine department inorder to reduce/prevent the morbidity and mortality of the patients through regular monitoring.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients with history of rodenticide poisoning with zinc phosphide in Emergency OPD Patient willing for study.
排除标准
- •Patient not willing for study Poisoning with unknown compound Patient less than 18 years of age and more than 70 years If zinc phosphide mixed with other poisons but not limited to alcohol Patient has preexisting liver pathology which includes acute/chronic hepatitis before ingestion.
- •Patient has preexisting renal pathology which includes acute chronic renal failure before ingestion.
- •History of psychiatric illness History of respiratory or cardiac diseases History of epilepsy or bleeding tendencies Treatment initiated before arriving to the emergency OPD.
结局指标
主要结局
To study the efficacy of N acetyl cysteine in management of zinc phosphide rodenticide poisoning in reducing morbidity and mortality in patients
时间窗: zero hrs at time of admission | 12hrs | 24hrs | 48hrs | 72hrs
次要结局
- To assess biochemical outcomes(Cardiac outcome with serial ECG studies)
研究者
Dr Siva K V
J.L.N Medical College Ajmer
研究点 (1)
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