Automatic vs. Manual Optic Disc Planimetry

Withdrawn

• Conditions: Open Angle Glaucoma
• Interventions: Other: manual planimetry; Other: automated planimetry

• Registration Number: NCT02438319
• Lead Sponsor: University of Zurich

Brief Summary

Manually and automatically by mashing learning algorithm optic disc will be evaluated (planimetry).

Detailed Description

Cross-Over non-randomized Case-Series. Arm 1 (Manual segmentation): Manually marking of the boundaries of the optic disc and it's excavation on color photographs of the optic disc. Arm 2 (Automated segmentation): Automatic detection of the boundaries of the optic disc and it's excavation. Calculation of cup size, size of excavation, cup-to-disc ratio, and rim area. Comparison of all parameters of both arms and computing of agreement.

Study Timeline

• Study First Submitted: 2015-04-29
• Study First Submitted QC: 2015-05-05
• Study First Posted: 2015-05-08
• Study Start: 2017-07-01
• Status Verified: 2020-03
• Primary Completion: 2020-03-20
• Study Completion: 2020-03-20
• Last Update Submitted: 2020-03-24
• Last Update Posted: 2020-03-26

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• open-angle glaucoma

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Exclusion Criteria

• no fundus photography of the optic disc performed

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patients with open angle glaucoma	automated planimetry	patients with open angle glaucoma who had their optic discs routinely documented by fundus photography. Optic disc photographs will be analyzied by manual planimetry or automated planimetry.
patients with open angle glaucoma	manual planimetry	patients with open angle glaucoma who had their optic discs routinely documented by fundus photography. Optic disc photographs will be analyzied by manual planimetry or automated planimetry.

Primary Outcome Measures

Name	Time	Method
agreement measured by kappa statistics	Baseline visit in the outpatient department	agreement measured by kappa statistics

Secondary Outcome Measures

Name	Time	Method
rim area	Baseline visit in the outpatient department	rim area
vertical cup to disc ratio	Baseline visit in the outpatient department	vertical cup to disc ratio
size of excavation	Baseline visit in the outpatient department	size of excavation
Cup size	Baseline visit in the outpatient department	Cup size