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Comparison of two antibiotics in the treatment of typhoid fever in children in General Hospital, Vavuniya

Not Applicable
Conditions
Typhoid fever
Registration Number
SLCTR/2010/001
Lead Sponsor
GH Vavuniya
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow up complete
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

All clinically suspected patients with Typhoid fever

Exclusion Criteria

1. Extremely unwell patients who are unable to tolerate oral fluids
2. Patients with complications of Typhoid fever such as intestinal hemorrhage, intestinal perforation or paralytic ileus
3. Known allergy to ampicillin or cotrimoxazole

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome measure will be the duration taken for the complete resolution of fever which is considered as maintaining normal body temperature for 48 hours or more, Development of adverse effects and disease related complications such as intestinal perforation, perforation or paralytic ileus will be assessed as secondary outcome measures [Day of fever free for 48 hours]<br>
Secondary Outcome Measures
NameTimeMethod
1. Development of adverse effects to antibiotics<br>2. Development of disease related complications [Daily assessment]<br>
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