MedPath

Resource Use and Disease Course in Dementia (REDIC)

Completed
Conditions
Neurodegenerative Diseases
Dementia
Registration Number
NCT01920100
Lead Sponsor
Sykehuset Innlandet HF
Brief Summary

This project is based on a three-year program that aims to improve the knowledge of the socioeconomic consequences of dementia in Norway. By including patients with and without dementia in four different cohorts (from nursing homes, from memory clinics, home-dwelling persons with dementia and elderly persons without dementia), the project's aim is to describe the course of dementia, the economical cost of dementia and to look into possible risk factors for dementia.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
696
Inclusion Criteria
  • All patients examined at a memory clinic with mild cognitive impairment or mild dementia
Exclusion Criteria
  • None

In-home care sample

Inclusion Criteria:

  • Persons 70 years of age or older receiving in-home care from the municipality

Exclusion Criteria:

  • None

Nursing-home sample

Inclusion Criteria:

  • All persons admitted to the nursing home with an expected stay of more than four weeks.
  • Participants should be 65 years or older, unless established dementia disease, in which case younger persons also will be included

Exclusion Criteria:

  • Life expectancy of less than six weeks

Control sample

Inclusion Criteria:

  • Persons 65 years or older without any sign of dementia

Exclusion Criteria:

  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cost of dementia3 years

The cost of dementia is assessed with the Resource Utilization in Dementia (RUD) (Wimo et al. 2009), for a period of three years for all the four cohorts. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Secondary Outcome Measures
NameTimeMethod
The course of neuropsychiatric symptoms3 years

The course of neuropsychiatric symptoms (depression, anxiety, psychosis, aggression, apathy, and cognition, are assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Quality of Life in persons admitted to nursing homes3 years

Quality of Life is assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Organizational factors of the nursing homesAt baseline

Organizational factors of the nursing homes and variables associated with the staff of the nursing homes will be collected at baseline, and the data will be used to explore associations between nursing home characteristics and the course of the symptoms in the patients.

DNA polymorphismAt baseline

DNA samples are collected for the nursing home cohort, and they are assessed for genetic polymorphism previous associated with dementia. The results are used as covariates in the analyses of the course of the symptoms and to look for risk factors for dementia.

Prescription of medication3 years

Prescription of medication is recorded at baseline, and the amount of medication used is recorded throughout the study period. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.

Trial Locations

Locations (3)

University of Bergen

🇳🇴

Bergen, Norway

Senter for omsorgsforskning - Midt

🇳🇴

Namsos, Norway

Innlandet Hospital Trust

🇳🇴

Ottestad, Norway

© Copyright 2025. All Rights Reserved by MedPath