JPRN-UMIN000016425已完成未知
The assessment of factor affecting toxicity of multikinase inhibitor pazopanib in soft tissue sarcoma - The assessment of factor affecting toxicity of pazopanib in soft tissue sarcoma
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 22
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Interstitial pneumonia, pulmonary fibrosis 2) Severe active infection 3) Serological positive for HBs-antigen or HCV-antibody 4) Previous therapy with pazopanib 5) Unstable angina or myocardial infarction within 3 months 6) Thrombosis (e.g., cerebral infarction, pulmonary infarction, deep venous thrombosis)within 6 months 7) Peptic ulcer within 6 months 8) Surgery within 28 days 9) Severe complication (e.g., uncontrollable diabetis mellitus, liver disease) 10) Active synchronous cancer 11) Severe psychiatric disorder 12) Pregnant or lactating women, or men and women without wanting pregnancy 13) Severe hypersensitivity to medicine 14) Taking medicine (e.g., phenytoin, carbamazepine, rifampicin, phenobarbital, ketokonazole, macrolide) affecting CYP3A4 within one week 15) Taking proton pump inhibitor or H2 blocker within one week 16) Patients who were judged inappropriate for the study
研究者
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