Neuropsychological Factors Associated With Vulnerability to Suicidal Behavior in Depressed Elderly Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 85
- 试验地点
- 2
- 主要终点
- Trust Game
研究概览
简要总结
The main objective of this study is to confirm the existence of risky decision making in a non strategic situation (Iowa Gambling Task) and a deficit of decision making in social situations, linked to greater sensitivity to injustice (Ultimatum Game) and a lower level of trust (Trust Game) in elderly depressed patients with a history of suicide attempts in comparison with older depressed patients without a history of suicidal acts and healthy subjects.
详细描述
The secondary objectives are to confirm or explore the deficits of certain cognitive processes involved in potentially suicidal behavior in depressed elderly persons but that have been little or not studied to date. These include:
A. cognitive control and sensitivity to interference (Victoria Stroop test, incompatibility test, flexibility test, Go / No-Go);
B. Strategic recovery of semantic memory (verbal fluency test);
C. Working memory (TEA);
D. Insight related to depression (Mood Disorders Insight Scale);
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Trust Game
时间窗: Days 1-7
Ultimatum Game
时间窗: Days 1-7
Iowa Gambling Task
时间窗: Days 1-7
次要结局
- Mood Disorders Insight Scale(Days 1-7)
- Cognitive Emotion Regulation Questionnaire(Days 1-7)
- Incompatibility Test(Days 1-7)
- Go-NoGo(Days 1-7)
- Bristol Emotion Recognition Test(Days 1-7)
- Balanced Temporal Perspective Scale(Days 1-7)
- Working memory - TEA(Days 1-7)
- Questionnaire on negative attitudes towards problems(Days 1-7)
- Suicide attempt within 6 months of follow-up(Month 6)
- Stroop Victoria Test(Days 1-7)
- Flexibility test(Days 1-7)
- Verbal fluency test(Days 1-7)
- Future autobiographical fluency task(Days 1-7)
- Revised self-awareness scale, Self-reference task(Days 1-7)