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Clinical Trials/NCT03205540
NCT03205540
Completed
N/A

Comparison Efficacy of Analgesic Techniques: Continuous Epidural Analgesia Versus Bilateral Single-shot Adductor Canal Blocks in Patients Undergoing Bilateral Total Knee Arthroplasty

Mahidol University1 site in 1 country70 target enrollmentAugust 1, 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Osteo Arthritis Knee
Sponsor
Mahidol University
Enrollment
70
Locations
1
Primary Endpoint
pain scores at rests
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study evaluates postoperative analgesic efficacy within 48 hours between epidural analgesia and single-shot bilateral adductor canal blocks in bilateral total knee arthroplasty. Half of participants will be received continuous epidural analgesia, while other half of participants will be received single-shot bilateral adductor canal blocks.

Detailed Description

Continuous epidural analgesia is effective postoperative pain control but it has some limitations in patients with hypotension, concurrent anticoagulants, technical difficulty, urinary retention. Adductor canal block is less invasive than continuous epidural analgesia. It provides effective analgesia for total knee arthroplasty and preserves quadriceps muscle strength.

Registry
clinicaltrials.gov
Start Date
August 1, 2017
End Date
May 1, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Suwimon Tangwiwat

Assistant professor, Anesthesiology department, Faculty of Medicine Siriraj Hospital

Mahidol University

Eligibility Criteria

Inclusion Criteria

  • Aged more than 18 years old undergoing bilateral total knee arthroplasty
  • American Society of Anesthesiologists physical status classification 1-3

Exclusion Criteria

  • Participants deny to enroll the study
  • Allergy to bupivacaine
  • Weight less than 50 kilograms
  • Hepatic disease
  • Contraincation for neuraxial block or adductor canal block
  • Uncontrolled cardiovascular disease
  • Creatinine clearance less than 50 ml/min

Outcomes

Primary Outcomes

pain scores at rests

Time Frame: 48 hours postoperatively

numerical rating scales

Secondary Outcomes

  • morphine consumptions(48 hours postoperatively)
  • pain scores on movement(48 hours postoperatively)
  • side effects of interventions(48 hours postoperatively)

Study Sites (1)

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