Comparison Efficacy of Analgesic Techniques: Continuous Epidural Analgesia Versus Bilateral Single-shot Adductor Canal Blocks in Patients Undergoing Bilateral Total Knee Arthroplasty
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- pain scores at rests
研究概览
简要总结
This study evaluates postoperative analgesic efficacy within 48 hours between epidural analgesia and single-shot bilateral adductor canal blocks in bilateral total knee arthroplasty. Half of participants will be received continuous epidural analgesia, while other half of participants will be received single-shot bilateral adductor canal blocks.
详细描述
Continuous epidural analgesia is effective postoperative pain control but it has some limitations in patients with hypotension, concurrent anticoagulants, technical difficulty, urinary retention.
Adductor canal block is less invasive than continuous epidural analgesia. It provides effective analgesia for total knee arthroplasty and preserves quadriceps muscle strength.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged more than 18 years old undergoing bilateral total knee arthroplasty
- •American Society of Anesthesiologists physical status classification 1-3
排除标准
- •Participants deny to enroll the study
- •Allergy to bupivacaine
- •Weight less than 50 kilograms
- •Hepatic disease
- •Contraincation for neuraxial block or adductor canal block
- •Uncontrolled cardiovascular disease
- •Creatinine clearance less than 50 ml/min
结局指标
主要结局
pain scores at rests
时间窗: 48 hours postoperatively
numerical rating scales
次要结局
- morphine consumptions(48 hours postoperatively)
- pain scores on movement(48 hours postoperatively)
- side effects of interventions(48 hours postoperatively)
研究者
Suwimon Tangwiwat
Assistant professor, Anesthesiology department, Faculty of Medicine Siriraj Hospital
Mahidol University