Comparison of anti-inflammatory dietary approaches on inflammation and muscle function in old adults

Not Applicable

• Conditions: M62.5; Muscle wasting and atrophy, not elsewhere classified

• Registration Number: DRKS00018995
• Lead Sponsor: Deutsches Institut für Ernährungsforschung (DIfE) Potsdam-Rehbrücke

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-14
• Study Completion: 2022-01-25
• Results First Posted: 2022-10-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

Montreal Cognitive Assessment (MoCA) = 26 points; age-adapted normal to light overweight (BMI 25-29,9 kg/m²); written informed consent

Exclusion Criteria

active smokers; acute, active infection of upper [ICD-10: J00-J06] or lower respiratory tract [ICD-10: J09-J18; J20-J22]; drastic, unintentional weight loss (> 5% last 6 months); (severe) food intolerances/allergies [ICD-10: T78] to milk/-products (in particular milk protein, whey protein, lactose), rosemary, blood orange, algae; acute herniated disc [ICD-10: M51]; diabetes mellitus type 1 and 2 [ICD-10: E10 and E11]; obesity (BMI =30 kg / m²) [ICD-10: E65-66]; dementia [ICD-10: F00-F03]; self-reported severe/active diseases of liver or kidney, rheumatic diseases as well as malignancies

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
at baseline and after 8 weeks of intervention: Chair rise test

Secondary Outcome Measures

Name	Time	Method
at baseline and after 8 weeks of intervention: - differences in cytokine profile - inflammatory response after LPS-stimulation - hand grip strength - knee extension strength - coordination (FTT) - physical performance (SPPB) - physical activity (accelerometry, IPAQ) - body composition (BodPod, BIA) - cognitive function (MoCA)