Effect of different concentration of oxygen given introperatively on postoperative gas exchange

Phase 2

Not yet recruiting

Conditions: Measurement and Monitoring,

Registration Number: CTRI/2020/12/029550

Brief Summary: The present observational study is planned to observe the effect of different fraction of inspired oxygen given intraoperatively on postoperative gas exchange as indicated by PaO2/FiO2 ratio, postoperative nausea and vomiting, and postoperative surgical site infection.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 1000

Inclusion Criteria

Patients belonging to American Society of Anesthesiologists (ASA) physical status grade I and II, 18-65 years of age scheduled for elective surgery under general anaesthesia will be enrolled.

Exclusion Criteria

Patients posted for or having history of cardio-thoracic surgery, use of intraoperative nitrous oxide, requirement of postoperative mechanical ventilation, patients with cardiac/respiratory disorders, morbid obesity (BMI >40 kg/m2), active upper or lower airway infection, abnormal preoperative chest Xâ€ray findings will be excluded.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To observe the effect of different fraction of inspired oxygen on postoperative PaO2/FIO2 ratio	Preoperatively, Postextubation, Postoperatively 1 hour

Secondary Outcome Measures

Name	Time	Method
To observe severity of atelectasis by lung ultrasound	Preoperatively, Postoperatively
To observe incidence of postoperative nausea and vomiting	Till 24 hour postoperatively
To observe incidence of surgical site infection	Postoperative Day 5

Trial Locations

Locations (1): AIIMS Jodhpur
🇮🇳
Jodhpur, RAJASTHAN, India
AIIMS Jodhpur
🇮🇳Jodhpur, RAJASTHAN, India
Kamlesh Kumari
Principal investigator
09780040150
kamlesh.gmch@gmail.com