跳至主要内容
临床试验/NCT05706415
NCT05706415招募中不适用

Enhanced Deep Learning Model for Diagnosis of Pancreatic Solid Lesions Through Multimodal Clinical Images

Changhai Hospital1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年1月21日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
200
试验地点
1
主要终点
Researchers use artificial intelligence (AI) support system to assist in diagnosis of pancreatic solid space-occupying lesions

研究概览

简要总结

Solid lesions of the pancreas mainly include tumor and non tumor lesions. More than 90% of pancreatic tumor lesions are pancreatic cancer, which is characterized by high mortality and poor prognosis and requires surgical treatment; Non-tumor lesions of the pancreas are mainly inflammatory lesions, which usually do not require surgical treatment, but can be treated with drugs. The common ones are chronic pancreatitis and autoimmune pancreatitis, with a good prognosis. Clinically, the differential diagnosis between them is very difficult. Multi-disciplinary diagnosis and treatment of MDT makes our understanding of pancreatic diseases increasingly rich and in-depth. From disease diagnosis to preoperative evaluation and curative effect evaluation, non-invasive imaging involves almost every link under MDT mode. In view of this, improving the differential diagnosis of pancreatic solid space-occupying lesions on imaging will be more conducive to the diagnosis and treatment under MDT mode, so new technologies such as artificial intelligence should be considered. Our goal is to develop a clinically applicable artificial intelligence system, which uses multiple modes to simulate the routine clinical workflow and assist in the diagnosis of benign and malignant pancreatic solid space-occupying lesions.

详细描述

The diagnosis of solid pancreatic lesions is challenging, MDT is a very effective method, but it has a certain misdiagnosis rate. This is a multi-center, prospective and observational clinical study. Our goal is to develop a clinically applicable artificial intelligence system. On the one hand, our artificial intelligence based on clinical data+CT imaging images can assist MDT doctors to diagnose the nature of pancreatic space-occupying lesions and reduce misdiagnosis; On the other hand, if a patient needs EUS-FNA puncture, the multimodal artificial intelligence system based on clinical data+CT+EUS developed by us can help MDT doctors understand the nature of pancreatic space-occupying lesions and reduce the probability of misdiagnosis or secondary puncture.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • pancreatic solid mass in CT and EUS

排除标准

  • insufficient imaging quality of CT or EUS
  • endoscopic ultrasound non accessible lesions

结局指标

主要结局

Researchers use artificial intelligence (AI) support system to assist in diagnosis of pancreatic solid space-occupying lesions

时间窗: 2 months

A multi-layer screening deep convolution network based on deep convolution network was developed to observe its accuracy, sensitivity and specificity in assisting MDT doctors to identify benign and malignant pancreatic space-occupying lesions.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验