Epicutaneous Testing of Cosmetics for Skin Compatibility

Not Applicable

Recruiting

• Conditions: Dermatitis
• Interventions: Other: Patch test application

• Registration Number: NCT03024671
• Lead Sponsor: Insel Gruppe AG, University Hospital Bern

Brief Summary

The dermatological testing of cosmetic products which are new on the market, or existing products with novel formulations is common and a useful procedure, yet necessary to alleviate common irritants and contact allergic reactions. Cosmetic products contain a range of substances that may be considered as potential irritants or contact allergens. In order to estimate that risk, cosmetics are tested by applying patch tests.

Detailed Description

The dermatological testing of cosmetic products which are new on the market, or existing products with novel formulations is common and a useful procedure, yet necessary to alleviate common irritants and contact allergic reactions. Cosmetic products contain a range of substances that may be considered as potential irritants or contact allergens. In order to estimate that risk, cosmetics are tested by applying patch tests, as with allergic reactions.

Study Timeline

• Study First Submitted: 2017-01-11
• Study First Submitted QC: 2017-01-16
• Study First Posted: 2017-01-19
• Study Start: 2017-02-10
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-14
• Last Update Posted: 2024-11-19
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

• Men and women older than 18 years old
• Persons undergoing a diagnostic patch test for reason of a skin disease
• Signed written informed consent

Exclusion Criteria

• Acute skin inflammation and eczema on the back
• Systemic corticosteroid and immunosuppressive therapy as well as UV exposure of the back within the last 4 weeks
• Topical corticosteroids used on the back within the last two weeks

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
patch test	Patch test application	Patients with patch test of cosmetics

Primary Outcome Measures

Name	Time	Method
Number of patients with positive patch test reactions to cosmetics	4 weeks	Inflammation of Skin at test patch location

Trial Locations

Locations (1)

Inselspital Bern; 🇨🇭 Bern, Switzerland