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The Role of Computed Tomography in the Phenotyping of COPD Patients

Completed
Conditions
COPD
Registration Number
NCT05747235
Lead Sponsor
Aswan University
Brief Summary

Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease that is characterized by respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases. the CT was used for classification of COPD patients into different phenotypes: phenotype A that has minimal emphysema with or without airway disease, phenotype E that has emphysema without airway disease, and finally phenotype M as a mixed form. The investigators aimed to to identify the phenotypes of COPD using radiologic data obtained by computed tomography. Moreover, this study will be designed to answer the questions about possible correlation between pulmonary function parameters and CT.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • All stable COPD patients that lastly confirmed to have the disease based on spirometry and past clinical history according to GOLD (2022).
  • Age above 18 years.
Exclusion Criteria
  • COPD patients associated with other chest diseases as collapse
  • COPD patients associated with consolidation
  • COPD patients unable to perform spirometry

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Identifying the different phenotypes of COPD using HRCTone month

Identifying the different phenotypes of COPD using HRCT. moreover, to identify whether there is a possible correlation between CT phenotypes and FEV1, FVC or FEV1/FVC.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Islam Galal Sayed

🇪🇬

Assiut, Egypt

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