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临床试验/NCT06176612
NCT06176612已完成不适用

In Patients With Crowe Type III and Crowe Type IV Hip Dysplasia, Mid-Term Lower Extremities and Spine After Total Hip Arthroplasty Natural Course

Bezmialem Vakif University2 个研究点 分布在 2 个国家目标入组 33 人开始时间: 2021年4月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
33
试验地点
2
主要终点
Mechanical axis deviation (MAD)

研究概览

简要总结

Patients with developmental hip dysplasia often present to the outpatient clinic in adulthood with hip pain due to progressive hip osteoarthritis. However, they may have complaints such as limping, lumbar lordosis, lower back pain, and leg length difference. Today, the best treatment option for these patients is hip arthroplasty. Hip arthroplasty causes a high rate of functional improvement and pain relief. According to the hip arthroplasty technique applied, improvement in lameness, leg length difference and spinal curvatures is expected. The aim of our study is to show the change in postoperative spine and lower extremity curvatures after hip arthroplasty in patients with advanced developmental hip dislocation.

详细描述

Developmental hip dysplasia (DDH) describes the spectrum of anatomical changes in the acetabulum and proximal femur; these can cause limping, lower back pain, lumbar lordosis, and leg length variation. DDH is the main cause of degenerative arthritis of the hip and valgus deformity of the knee. The best treatment option for DDH is total hip arthroplasty (THA). During THA, the distorted anatomy of the acetabulum and proximal femur poses great difficulties. Additionally, the soft tissue can be released and the femur can be shortened while correcting the placement of the acetabulum to prevent neurological damage (sciatic nerve paralysis). Postoperative evaluations focused on assessing joint function and alleviating preoperative clinical symptoms. Some studies have examined changes in lower extremity and knee alignment after THA in patients with DDH. In patients with DDH, THA may cause genu valgus deformity due to increased lower extremity length and Q angle immediately after the operation. THA extends the lower extremity, affecting the patellofemoral joint and anterior knee pain. However, the long-term effects of THA on the alignment of the lower extremity are unclear, especially in patients with Crowe type III and IV DDH, which involves femoral shortening osteotomy. There are few studies examining changes in the knee and lower extremities as a result of THA in patients with DDH. The aim of this study is to evaluate the mid- and long-term alignment of the spine and lower extremity after THA with or without femoral shortening osteotomy in patients with unilateral DDH (Crowe type III-IV).

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients with unilateral Crowe type 3 hip dysplasia
  • Patients with unilateral Crowe type 4 hip dysplasia

排除标准

  • Patients with unilateral Crowe type 1 hip dysplasia
  • Patients with unilateral Crowe type 2 hip dysplasia
  • History of previous surgery on the hip for which surgery is planned

结局指标

主要结局

Mechanical axis deviation (MAD)

时间窗: From enrollment to the end of treatment at 2 years

the lower limb was defined as the distance from the center of the knee to the mechanical axis of the lower limb

次要结局

  • The medial proximal tibial angle (MPTA)(From enrollment to the end of treatment at 2 years)
  • The femoral offset (FO)(From enrollment to the end of treatment at 2 years)
  • tibiofemoral angle (TFA)(From enrollment to the end of treatment at 2 years)
  • The hip-knee-ankle angle (HKA)(From enrollment to the end of treatment at 2 years)
  • The lateral distal femoral angle (LDFA)(From enrollment to the end of treatment at 2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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